Structure of PDB 7f1u Chain C

Receptor sequence
>7f1uC (length=392) Species: 303 (Pseudomonas putida) [Search protein sequence]
LPGFATRAIHHGYDPQDHGGALVPPVYQTATFTFPTVEYGAACFAGEQAG
HFYSRISNPTLNLLEARMASLEGGEAGLALASGMGAITSTLWTLLRPGDE
VLLGNTLYGCTFAFLHHGIGEFGVKLRHVDMADLQALEAAMTPATRVIYF
ESPANPNMHMADIAGVAKIARKHGATVVVDNTYCTPYLQRPLELGADLVV
HSATKYLSGHGDITAGIVVGSQALVDRIRLQGLKDMTGAVLSPHDAALLM
RGIKTLNLRMDRHCANAQVLAEFLARQPQVELIHYPGLASFPQYTLARQQ
MSQPGGMIAFELKGGIGAGRRFMNALQLFSRAVSLGDAESLASHPASMTH
SSYTPEERAHYGISEGLVRLSVGLEDIDDLLADVQQALKASA
3D structure
PDB7f1u Characterization and application of l-methionine gamma-lyase Q349S mutant enzyme with an enhanced activity toward l-homocysteine.
ChainC
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.4.1.11: methionine gamma-lyase.
4.4.1.2: homocysteine desulfhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3LM C G89 M90 Y114 N161 D186 S208 T210 K211 S340 T355 R375 G83 M84 Y108 N155 D180 S202 T204 K205 S334 T349 R369
BS02 3LM C Y59 R61 Y53 R55
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0016846 carbon-sulfur lyase activity
GO:0018826 methionine gamma-lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0047982 homocysteine desulfhydrase activity
Biological Process
GO:0019346 transsulfuration
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:7f1u, PDBe:7f1u, PDBj:7f1u
PDBsum7f1u
PubMed34953671
UniProtP13254|MEGL_PSEPU L-methionine gamma-lyase (Gene Name=mdeA)

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