Structure of PDB 7eps Chain C

Receptor sequence

>7epsC (length=310) Species: 32630 (synthetic construct) [Search protein sequence]

PKILIIGANGQIGSELALALAERYGRENVIASDVVPTGRHVHLPFEVLNA
TDRGELATVVERHGITQVYLLAAALSATGEKAPQWAWNLNMTSLLNVLEL
ARQTGLEKIFWPSSIAAFGPTTPAGQTPQKTVMEPTTVYGISKQAGEGWC
RWYHANHGVDVRSIRYPGLISHKTPPGGGTTDYAVDIFHAAVTGEPYTCF
LKEDEALPMMYMPDAIRATIELMEAPADKLSERGSYNIAGMSFTPAQIAA
AIREQVPGFQIRYEPDYRQAIAQGWPDSIDDSVARADWGWKAQYGLKEMV
ADMLANLKAT

3D structure

PDB

7eps Partial Consensus Design and Enhancement of Protein Function by Secondary-Structure-Guided Consensus Mutations.

Chain

Resolution

2.102 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAD	C	N14 G15 Q16 I17 D38 V39 L53 A55 L76 A77 A78 L94 P117 Y144 K148 Y171 L174	N9 G10 Q11 I12 D33 V34 L48 A50 L71 A72 A73 L89 P112 Y139 K143 Y166 L169
BS02	THR	C	S81 S119 Y144 G184 T185 T186	S76 S114 Y139 G179 T180 T181

External links

PDB	RCSB:7eps, PDBe:7eps, PDBj:7eps
PDBsum	7eps
PubMed	34254784

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