Structure of PDB 7eby Chain C

Receptor sequence

>7ebyC (length=762) Species: 1744839 (Cupriavidus sp. P4-10-C)

PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQI
DLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVA
EAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTL
NFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAA
LKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSL
RYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYE
TDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHAD
DASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQ
VYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAY
NPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSS
LRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRG
WDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLA
VLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIF
RHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRM
VLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVE
RAAEKRIELTPR

3D structure

• PDB: 7eby Protein Engineering of d-Succinylase from Cupriavidus sp. for d-Amino Acid Synthesis and the Structural Implications.
• Chain: C
• Resolution: 2.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CO3	C	S282 H304 R350 N523	S220 H242 R288 N461
BS02	CO3	C	R305 R313 L348 Y433 E460	R243 R251 L286 Y371 E398
BS03	CA	C	N165 E169 D354 E356 D357 G487	N151 E155 D292 E294 D295 G425

Gene Ontology

Molecular Function

• GO:0016787 hydrolase activity
• GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

Biological Process

• GO:0017000 antibiotic biosynthetic process

External links

• PDB: RCSB:7eby, PDBe:7eby, PDBj:7eby
• PDBsum: 7eby
• UniProt: A0A0N7KZ58