Structure of PDB 7e1s Chain C

Receptor sequence

>7e1sC (length=366) Species: 210 (Helicobacter pylori) [Search protein sequence]

HHHMVSTLKPLKIGKHTIKFPIFQGGMGVGISWDELAGNVAKEGALGVIS
AVGTGYYKNMRFVERIVAKKPFEALNFYSKKALNEIFANARKICGNNPLG
ANILYAINDYGRVLRDSCEAGANIIITGAGLPTNMPEFAKDFSDVALIPI
ISSAKALKILCKRWSDRYKRIPDAFIVEGPLSGGHQGFKYEDCFKEEFRL
ENLVPKVVEASKEWGNIPIIAAGGIWDRKDIDTMLSLGASGVQMATRFLG
TKECDAKVYADLLPTLKKEDILLIKSPVGYPARAINTGVIKRIEEGNAPK
IACVSNCVAPCNRGEEAKKVGYCIADGLGRSYLGNREEGLYFTGANGYRV
DKIISVHELIKELTEG

3D structure

PDB

7e1s Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis.

Chain

Resolution

2.31 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	C	L128 T130 N131 K152 I156 K159 R160 R164	L131 T133 N134 K155 I159 K162 R163 R167
BS02	FMN	C	G22 G23 M24 G25 N99 E175 S179 G180 G220 G221 M241 A242 T243 L246 F339 T340	G25 G26 M27 G28 N102 E178 S182 G183 G223 G224 M244 A245 T246 L249 F342 T343
BS03	SF4	C	C300 N303 C304 V305 C308 G311 A314 C320 I321	C303 N306 C307 V308 C311 G314 A317 C323 I324
BS04	66S	C	L101 A126 G127 L128 I147 I148 S149 E175 H182 Y277 I321 L325	L104 A129 G130 L131 I150 I151 S152 E178 H185 Y280 I324 L328

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0018580	nitronate monooxygenase activity
GO:0046872	metal ion binding
GO:0051539	4 iron, 4 sulfur cluster binding

View graph for
Molecular Function

External links

PDB	RCSB:7e1s, PDBe:7e1s, PDBj:7e1s
PDBsum	7e1s
PubMed	34836944
UniProt	B5Z7D6

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