Structure of PDB 7e1r Chain C

Receptor sequence

>7e1rC (length=366) Species: 210 (Helicobacter pylori) [Search protein sequence]

HHHMVSTLKPLKIGKHTIKFPIFQGGMGVGISWDELAGNVAKEGALGVIS
AVGTGYYKNMRFVERIVAKKPFEALNFYSKKALNEIFANARKICGNNPLG
ANILYAINDYGRVLRDSCEAGANIIITGAGLPTNMPEFAKDFSDVALIPI
ISSAKALKILCKRWSDRYKRIPDAFIVEGPLSGGHQGFKYEDCFKEEFRL
ENLVPKVVEASKEWGNIPIIAAGGIWDRKDIDTMLSLGASGVQMATRFLG
TKECDAKVYADLLPTLKKEDILLIKSPVGYPARAINTGVIKRIEEGNAPK
IACVSNCVAPCNRGEEAKKVGYCIADGLGRSYLGNREEGLYFTGANGYRV
DKIISVHELIKELTEG

3D structure

PDB

7e1r Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis.

Chain

Resolution

2.795 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	FMN	C	G22 G23 M24 G25 N99 L101 E175 G180 G220 G221 M241 A242 T243 F339	G25 G26 M27 G28 N102 L104 E178 G183 G223 G224 M244 A245 T246 F342
BS02	SF4	C	C300 N303 C304 V305 C308 G311 C320 I321	C303 N306 C307 V308 C311 G314 C323 I324
BS03	PN7	C	G125 A126 G127 I147 E175 H182 G184	G128 A129 G130 I150 E178 H185 G187

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0018580	nitronate monooxygenase activity
GO:0046872	metal ion binding
GO:0051539	4 iron, 4 sulfur cluster binding

View graph for
Molecular Function

External links

PDB	RCSB:7e1r, PDBe:7e1r, PDBj:7e1r
PDBsum	7e1r
PubMed	34836944
UniProt	B5Z7D6

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