Structure of PDB 7cqu Chain C

Receptor sequence

>7cquC (length=429) Species: 2203891 (Rhodovulum sp. 12E13)

TDLASIAREKGIEFFLISFTDLLGVQRAKLVPARAIADMAVNGAGFAGFA
AWLDMSPADADILAIPDPESLIQLPWKPSVGWLAADVHFEGRPFPKAPRV
ALKSVLARAAGKDMHLKHGVECEFFLIQPDGSAISDPADTQAKPCYDQDA
LMRRFDVIAEICSYMVDLGWGPYQNDHEDANGQFEMNWDYADALVTADRH
AFFKFMVKSVAERHGLRATFMPKPFAHLTGNGCHTHLSMWTAAGDNLFEG
DGELGLSPTAYAFLGGLIGHAKGLTAVVNPTVNSYKRLNAPVTVSGATWS
PNTITYGGNNRTHMVRIPDAGRLELRLPDGAANPYLMPAAILAAGLDGIE
TQADPGQRLDIDMYVEGHSVEAEQLPLNLLDAVRALEADEVLAGGLGAAA
AAFAKFKRAEWADYKSQLTEWERRTTLDC

3D structure

• PDB: 7cqu Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
• Chain: C
• Resolution: 2.06 Å

Enzymatic activity

• Enzyme Commision number: 6.3.1.2: glutamine synthetase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MG	C	E122 E186	E121 E185
BS02	MG	C	E122 H235 E325	E121 H234 E324
BS03	MG	C	E124 E179 E186	E123 E178 E185
BS04	ADP	C	E122 Y174 N188 D190 Y191 H237 L238 S239 R317 R323	E121 Y173 N187 D189 Y190 H236 L237 S238 R316 R322
BS05	P3S	C	E122 E124 E179 E186 T230 G231 H235 R288 W300 R312 R327	E121 E123 E178 E185 T229 G230 H234 R287 W299 R311 R326

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003824 catalytic activity
• GO:0004356 glutamine synthetase activity
• GO:0016874 ligase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006542 glutamine biosynthetic process
• GO:0009399 nitrogen fixation

External links

• PDB: RCSB:7cqu, PDBe:7cqu, PDBj:7cqu
• PDBsum: 7cqu
• PubMed: 33199371
• UniProt: A0A369R1N0