Structure of PDB 7ccq Chain C

Receptor sequence
>7ccqC (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
TRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILEL
AGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVL
LP
3D structure
PDB7ccq Structural basis for nucleosome-mediated inhibition of cGAS activity.
ChainC
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C T16 R17 R20 G28 R32 R42 T1 R2 R5 G13 R17 R27
BS02 dna C R29 R42 V43 G44 A45 T76 R77 R14 R27 V28 G29 A30 T61 R62
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ccq, PDBe:7ccq, PDBj:7ccq
PDBsum7ccq
PubMed33051594
UniProtP04908|H2A1B_HUMAN Histone H2A type 1-B/E (Gene Name=H2AC4)

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