Structure of PDB 7atu Chain C

Receptor sequence
>7atuC (length=244) Species: 9606 (Homo sapiens) [Search protein sequence]
FGQAIVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYLNFI
TEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLN
SHNCLVRENKNVVVADFGLARLMNPYWMAPEMINGRSYDEKVDVFSFGIV
LCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCD
LDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETY
3D structure
PDB7atu The LIMK1 Kinase Domain Bound To LIJTF500025
ChainC
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D460 N462 H464 N465 D478 N512
Catalytic site (residue number reindexed from 1) D98 N100 H102 N103 D116 N124
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RXN C A353 V366 K368 M388 L391 L397 F411 T413 L451 I456 A477 D478 F479 R483 A4 V8 K10 M30 L33 L39 F49 T51 L89 I94 A115 D116 F117 R121
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7atu, PDBe:7atu, PDBj:7atu
PDBsum7atu
PubMed
UniProtP53667|LIMK1_HUMAN LIM domain kinase 1 (Gene Name=LIMK1)

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