Structure of PDB 7a09 Chain C

Receptor sequence
>7a09C (length=633) Species: 9606 (Homo sapiens) [Search protein sequence]
RVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSI
VDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIR
KYNAAAAAAAAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLV
QIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINEL
MDILFANPNIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKI
MQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRIL
HTYYKFDYKAHSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRW
YQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNA
LLDIQSSGRAKELLGQGLNQEQEKVERRRQVPFHLHINLELLECVYLVSA
MLLEIPYMAAHERMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMK
MGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTY
SSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMH
RTEPTAQQNLALQLAEKLGSLVENNERVFDHKQ
3D structure
PDB7a09 A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
ChainC
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C R47 V49 K55 R56 K92 W121 N131 K132 K136 S139 T140 Q143 R1 V3 K9 R10 K46 W75 N85 K86 K90 S93 T94 Q97
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0031369 translation initiation factor binding
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005852 eukaryotic translation initiation factor 3 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7a09, PDBe:7a09, PDBj:7a09
PDBsum7a09
PubMed33289941
UniProtQ99613|EIF3C_HUMAN Eukaryotic translation initiation factor 3 subunit C (Gene Name=EIF3C)

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