Structure of PDB 6zy0 Chain C

Receptor sequence

>6zy0C (length=696) Species: 391937 (Nitratireductor pacificus pht-3B)

AQISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSL
LGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVG
ICRLDPDGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRC
AEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAP
FLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDA
EEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDL
GEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDP
GRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVM
LIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARS
HSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSQSIVFTTDLPMS
VDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCT
KYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMD
DALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQK
LAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKS

3D structure

• PDB: 6zy0 Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope.
• Chain: C
• Resolution: 2.13 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	SF4	C	R473 I474 L479 F511 C512 C515 C518 C568 P569 W570	R474 I475 L480 F512 C513 C516 C519 C569 P570 W571
BS02	SF4	C	C522 P523 I527 C548 C561 C564	C523 P524 I528 C549 C562 C565
BS03	B12	C	D289 F290 F291 Y379 Y426 I458 H459 N460 P461 I463 I474 D476 T477 L478 S487 Q488 S489 F535 Y538 K542 T549 R552	D290 F291 F292 Y380 Y427 I459 H460 N461 P462 I464 I475 D477 T478 L479 S488 Q489 S490 F536 Y539 K543 T550 R553

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding
• GO:0051539 4 iron, 4 sulfur cluster binding

External links

• PDB: RCSB:6zy0, PDBe:6zy0, PDBj:6zy0
• PDBsum: 6zy0
• PubMed: 32887524
• UniProt: K2MB66