Structure of PDB 6zxu Chain C

Receptor sequence

>6zxuC (length=692) Species: 391937 (Nitratireductor pacificus pht-3B)

QISMRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLL
GDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGI
CRLDPDDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIA
AILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRR
GFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEK
RPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKA
KQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNA
EAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQ
GYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNA
HSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRP
IDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRV
TQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQ
NGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMY
PPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKS

3D structure

• PDB: 6zxu Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope.
• Chain: C
• Resolution: 1.73 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	SF4	C	R473 L479 F511 C512 C515 C518 C568 P569 W570	R470 L476 F508 C509 C512 C515 C565 P566 W567
BS02	SF4	C	C522 P523 I527 C548 C561 C564	C519 P520 I524 C545 C558 C561
BS03	B12	C	D289 F290 F291 Y379 Y426 I458 H459 N460 I463 I474 D476 T477 L478 K488 S489 F535 Y538 K542 C548 T549 R552	D286 F287 F288 Y376 Y423 I455 H456 N457 I460 I471 D473 T474 L475 K485 S486 F532 Y535 K539 C545 T546 R549

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding
• GO:0051539 4 iron, 4 sulfur cluster binding

External links

• PDB: RCSB:6zxu, PDBe:6zxu, PDBj:6zxu
• PDBsum: 6zxu
• PubMed: 32887524
• UniProt: K2MB66