Structure of PDB 6yuf Chain C

Receptor sequence
>6yufC (length=456) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
YITKIVIQGFKSYKDYTVIEPLSPHHNVIVGRNGSGKSNFFAAIRFVLSD
AYTHLSREERQALLHEGPGATVMSAYVEVTFANADNRFPTGKSEVVLRRT
IGLKKDEYSLDKKTVSKTEVINLLESAGFSRSNPYYIVPQGRVTSLTNAK
DSERLELLKEVAGTQIYENRRAESNKIMDETIQKSEKIDELLQYIEERLR
ELEEEKNDLAVYHKKDNERRCLEYAIYSREHDEINSVLDSSNAIVKKLHK
INEALKDYGSVNKKAYEQFNNFTKQRDSLLARREELRRSQESISELTTVL
DQRKDEAIERTFKQVAKSFSEIFVKLVPAGRGELVMNRRSISIRVSFNSK
DDEQLNINQLSGGQKSLCALTLIFAIQRCDPAPFNILDECDANLDAQYRS
AIAAMVKEMSKTSQFICTTFRPEMVKVADNFYGVMFNHKVSTVESISKEE
AMAFVE
3D structure
PDB6yuf A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
ChainC
Resolution3.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C L56 K118 L55 K117
BS02 ADP C Q1096 L1097 S1098 Q359 L360 S361
BS03 BEF C S39 Q141 S38 Q140
BS04 ADP C S13 N34 G35 S36 G37 K38 S39 N40 L65 S12 N33 G34 S35 G36 K37 S38 N39 L64
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0061776 topological DNA co-entrapment activity
Biological Process
GO:0007064 mitotic sister chromatid cohesion
GO:0031619 homologous chromosome orientation in meiotic metaphase I
GO:0051276 chromosome organization
GO:0051301 cell division
GO:0140588 chromatin looping
Cellular Component
GO:0000779 condensed chromosome, centromeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005829 cytosol
GO:0008278 cohesin complex
GO:0030892 mitotic cohesin complex
GO:0030893 meiotic cohesin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6yuf, PDBe:6yuf, PDBj:6yuf
PDBsum6yuf
PubMed32755595
UniProtO42649|SMC3_SCHPO Structural maintenance of chromosomes protein 3 (Gene Name=psm3)

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