Structure of PDB 6xwg Chain C

Receptor sequence
>6xwgC (length=79) Species: 9606 (Homo sapiens) [Search protein sequence]
KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDK
RQRNRCQYCRYQKCLAMGMKREAVQEERQ
3D structure
PDB6xwg Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
ChainC
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K145 H146 Y147 K160 R164 R172 Q206 E208 R209 K14 H15 Y16 K29 R33 R41 Q75 E77 R78
BS02 dna C E153 G154 R161 R184 N185 R191 E22 G23 R30 R53 N54 R60
BS03 ZN C C135 C138 C152 C155 C4 C7 C21 C24
BS04 ZN C C171 C177 C187 C40 C46 C56
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6xwg, PDBe:6xwg, PDBj:6xwg
PDBsum6xwg
PubMed32974652
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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