Structure of PDB 6x3j Chain C

Receptor sequence
>6x3jC (length=209) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
HGPDPENILPIKGNRNLQFIKPTITNENILVGEYSYYDSKRGESFEDQVL
YHYEVIGDKLIIGRFCSIGPGTTFIMNGANHRMDGSTYPFHLFRMGWEKY
MPSLKDLPLKGDIEIGNDVWIGRDVTIMPGVKIGDGAIIAAEAVVTKNVA
PYSIVGGNPLKFIRKRFSDGVIEEWLALQWWNLDMKIINENLPFIINGDI
EMLKRKRKL
3D structure
PDB6x3j Synthetic group A streptogramin antibiotics that overcome Vat resistance.
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 O7V C Y57 Y59 H87 H97 R100 M107 P108 L113 Y51 Y53 H81 H91 R94 M101 P102 L107
BS02 MG C N164 P165 N158 P159
BS03 SXA C Y57 H87 M134 Y51 H81 M128
BS04 SXA C W126 G128 R129 A146 A147 R170 W120 G122 R123 A140 A141 R164
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function

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Biological Process
External links
PDB RCSB:6x3j, PDBe:6x3j, PDBj:6x3j
PDBsum6x3j
PubMed32968273
UniProtP26839|VATA_STAAU Virginiamycin A acetyltransferase (Gene Name=vat)

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