Structure of PDB 6wk0 Chain C

Receptor sequence
>6wk0C (length=317) Species: 9606 (Homo sapiens) [Search protein sequence]
EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAA
RLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIV
NNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEA
LTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGS
AADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVD
TTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPY
KKDLPLTLFLEHHHHHH
3D structure
PDB6wk0 Crystal structures of human ribokinase
ChainC
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.15: ribokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RIB C M25 D27 G53 K54 N57 A109 E154 G266 D269 M12 D14 G40 K41 N44 A96 E141 G253 D256
BS02 ACP C N199 T235 G237 A238 G240 V259 A267 G268 N295 A298 A299 V302 N186 T222 G224 A225 G227 V246 A254 G255 N282 A285 A286 V289
Gene Ontology
Molecular Function
GO:0004747 ribokinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006014 D-ribose metabolic process
GO:0006098 pentose-phosphate shunt
GO:0006753 nucleoside phosphate metabolic process
GO:0016310 phosphorylation
GO:0019303 D-ribose catabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wk0, PDBe:6wk0, PDBj:6wk0
PDBsum6wk0
PubMed
UniProtQ9H477|RBSK_HUMAN Ribokinase (Gene Name=RBKS)

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