Structure of PDB 6wfq Chain C

Receptor sequence
>6wfqC (length=228) Species: 562 (Escherichia coli) [Search protein sequence]
NLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRP
SVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGG
IAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIR
SDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVSYQ
QHIAIVDAIRRHDPDEADRALQSHLNSV
3D structure
PDB6wfq Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.
ChainC
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K31 G68 K11 G48
BS02 dna C S57 E58 R73 G90 S37 E38 R53 G70
Gene Ontology
Molecular Function
GO:0001046 core promoter sequence-specific DNA binding
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
GO:0031334 positive regulation of protein-containing complex assembly
GO:0045892 negative regulation of DNA-templated transcription
GO:2000143 negative regulation of DNA-templated transcription initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:6wfq, PDBe:6wfq, PDBj:6wfq
PDBsum6wfq
PubMed33790291
UniProtP0A8W0|NANR_ECOLI HTH-type transcriptional repressor NanR (Gene Name=nanR)

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