Structure of PDB 6wea Chain C

Receptor sequence
>6weaC (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
TSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSA
RSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFK
IDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPP
DESIDLYQVIHKM
3D structure
PDB6wea Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA.
ChainC
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K361 S362 N363 N367 W377 S378 R404 E405 G407 W428 G433 F455 K472 I473 G474 R475 D476 K17 S18 N19 N23 W33 S34 R60 E61 G63 W84 G89 F111 K128 I129 G130 R131 D132
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6wea, PDBe:6wea, PDBj:6wea
PDBsum6wea
PubMed32663306
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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