Structure of PDB 6w7o Chain C

Receptor sequence
>6w7oC (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
GSSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCF
CCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQG
3D structure
PDB6w7o Structural Characterization of BTK:PROTAC:cIAP Ternary Complexes: From Snapshots to Ensembles
ChainC
Resolution2.17 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TL7 C D303 G312 L313 R314 C315 W316 D320 E325 W329 D46 G55 L56 R57 C58 W59 D63 E68 W72
BS02 ZN C C306 C309 H326 C333 C49 C52 H69 C76
External links
PDB RCSB:6w7o, PDBe:6w7o, PDBj:6w7o
PDBsum6w7o
PubMed
UniProtQ13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Gene Name=BIRC2)

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