Structure of PDB 6w6i Chain C

Receptor sequence
>6w6iC (length=624) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEP
GVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEER
LKAVLDDIKNSAGQIITFIDELHTIVGAGATAMDAGNMIKPMLARGELRL
VGATTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVH
HGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPV
EIDEVERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTT
RWQNEKNAKEEVGPDDIADVVSAWTGIPAGRLLEGETAKLLRMEDELGKR
VIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKALA
DFLFDDERAMVRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTEAVRRR
PYTVVLFDEIEKAHPDVFDVLLQVLDEGRLTDGHGRTVDFRNTILILTSN
LGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVDIQLAQ
LGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQAIGDQLAK
MLLAGQVHDGDTVPVNVSPDADSL
3D structure
PDB6w6i Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
ChainC
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C K250 G654 Y655 V656 K92 G433 Y434 V435
BS02 AGS C R571 I573 G610 V611 G612 K613 T614 E615 R805 R350 I352 G389 V390 G391 K392 T393 E394 R584
BS03 AGS C I181 G209 G211 K212 T213 I350 I23 G51 G53 K54 T55 I189
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w6i, PDBe:6w6i, PDBj:6w6i
PDBsum6w6i
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

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