Structure of PDB 6w6e Chain C

Receptor sequence
>6w6eC (length=624) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEP
GVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEER
LKAVLDDIKNSAGQIITFIDELHTIVGAGATAMDAGNMIKPMLARGELRL
VGATTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVH
HGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPV
EIDEVERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTT
RWQNEKNAKEEVGPDDIADVVSAWTGIPAGRLLEGETAKLLRMEDELGKR
VIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKALA
DFLFDDERAMVRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTEAVRRR
PYTVVLFDEIEKAHPDVFDVLLQVLDEGRLTDGHGRTVDFRNTILILTSN
LGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVDIQLAQ
LGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQAIGDQLAK
MLLAGQVHDGDTVPVNVSPDADSL
3D structure
PDB6w6e Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
ChainC
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C K250 Y251 G654 Y655 V656 K92 Y93 G433 Y434 V435
BS02 AGS C R332 R333 R171 R172
BS03 AGS C V572 I573 T609 V611 G612 K613 T614 R805 R808 V351 I352 T388 V390 G391 K392 T393 R584 R587
BS04 AGS C I181 G209 G211 K212 I23 G51 G53 K54
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w6e, PDBe:6w6e, PDBj:6w6e
PDBsum6w6e
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

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