Structure of PDB 6w3z Chain C

Receptor sequence
>6w3zC (length=352) Species: 6279 (Brugia malayi) [Search protein sequence]
DVHIAEMSVLKKSSTMPADSTIIKGYDFNEGINYDALLDQYMSTGFQASH
FAQAVQQINTMLTIREEQFEGDHTLPYPEGKQKRACTIFLGYTSNLVTSG
VRENIRYLVEHDLVDCIVTSAGGVEEDLIKCLAPSYLGAFDLDGKTLRHN
GLNRAGNIIIPNNNYCQFEDWLMPILDSCELEQKNNDFSWTPSKLIDRLG
AEINDKRSICYWAHRNRIPVFSPALTDGSIGDMLYFHSFRNGGIKLDIVE
DLRHINTMAVRSNRTGVILLGGGVMKHHINNANLMRNGSDYAVYVNTGQE
FDGSDSGARPDEAVSWGKVRSDCRPVKIYADATLVFPLLVAKTFARHVQQ
KH
3D structure
PDB6w3z Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD C H286 D311 S313 D314 S315 H277 D302 S304 D305 S306
BS02 NAD C T102 S103 N104 S129 A130 G131 D236 G280 G281 N305 T306 G307 D340 A341 T93 S94 N95 S120 A121 G122 D227 G271 G272 N296 T297 G298 D331 A332
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0034038 deoxyhypusine synthase activity
Biological Process
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w3z, PDBe:6w3z, PDBj:6w3z
PDBsum6w3z
PubMed33044977
UniProtA0A0J9XTC4

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