Structure of PDB 6w1i Chain C

Receptor sequence
>6w1iC (length=192) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
NAMEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAK
DGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYS
FTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIA
GIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQ
3D structure
PDB6w1i Molecular Mechanism of Regulation of the Purine Salvage Enzyme XPRT by the Alarmones pppGpp, ppGpp, and pGpp.
ChainC
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.22: xanthine phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G4P C L20 E58 S60 K81 S98 F99 T100 F126 N129 K156 L22 E60 S62 K83 S100 F101 T102 F128 N131 K158 MOAD: Kd=0.95uM
BS02 G4P C R80 L85 R82 L87 MOAD: Kd=0.95uM
Gene Ontology
Molecular Function
GO:0000310 xanthine phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0032265 XMP salvage
GO:0043101 purine-containing compound salvage
GO:0046110 xanthine metabolic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6w1i, PDBe:6w1i, PDBj:6w1i
PDBsum6w1i
PubMed32446804
UniProtP42085|XPT_BACSU Xanthine phosphoribosyltransferase (Gene Name=xpt)

[Back to BioLiP]