Structure of PDB 6vrx Chain C

Receptor sequence
>6vrxC (length=108) Species: 36080 (Mucor circinelloides) [Search protein sequence]
MGVTVERIAPGDGKNFPKKGDKVTIHYVGTLENGDKFDSSRDRGSPFQCT
IGVGQVIKGWDEGVTQLSVGEKARLICTHDYAYGERGYPGLIPPKATLNF
EVELIKIN
3D structure
PDB6vrx Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs.
ChainC
Resolution2.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FK5 C Y27 F37 D38 F47 V56 W60 Y83 Y27 F37 D38 F47 V56 W60 Y83
BS02 FK5 C P89 G90 L91 P89 G90 L91
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vrx, PDBe:6vrx, PDBj:6vrx
PDBsum6vrx
PubMed34809463
UniProtU3N5X4

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