Structure of PDB 6vlg Chain C

Receptor sequence
>6vlgC (length=468) Species: 10090 (Mus musculus) [Search protein sequence]
GLGKDHEILRRRIENGAKELWFFLQSELKKLKHLEGNELQRHADEILLDL
GHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSK
ARKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWE
TVFRPVSETCTDRSGLSTGHWSGEVNDKNIQVVELPIVDSLHPRPPYLPL
AVPEDLADRLLRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFK
HPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYL
ATDDPTLLKEAKTKYSNYEFISDNSISWSAGLHNRYTENSLRGVILDIHF
LSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHN
QIAVYPHKPRTEEEIPMEPGDIIGVAGNHWDGYSKGINRKLGKTGLYPSY
KVREKIETVKYPTYPEAE
3D structure
PDB6vlg Structural basis of substrate recognition and catalysis by fucosyltransferase 8.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.68: glycoprotein 6-alpha-L-fucosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP C G219 Y220 G221 C222 Y250 H363 R365 K369 T408 R441 V450 D453 S469 Q470 V471 G113 Y114 G115 C116 Y144 H257 R259 K263 T302 R335 V344 D347 S363 Q364 V365
Gene Ontology
Molecular Function
GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0016020 membrane
GO:0032580 Golgi cisterna membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vlg, PDBe:6vlg, PDBj:6vlg
PDBsum6vlg
PubMed32220931
UniProtQ9WTS2|FUT8_MOUSE Alpha-(1,6)-fucosyltransferase (Gene Name=Fut8)

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