Structure of PDB 6vel Chain C

Receptor sequence
>6velC (length=209) Species: 9606,559292 [Search protein sequence]
DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGV
FIIERETGWLKVTEPLDRERIATYTLFSHAGNAVEDPMEILITVTDQNDN
KPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQD
PELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTT
ATAVITVTD
3D structure
PDB6vel Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography.
ChainC
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C E112 D168 E170 D204 E11 D67 E69 D99
BS02 CA C N203 N205 D235 D237 N244 D296 N98 N100 D130 D132 N139 D191
BS03 CA C E112 E170 D201 Q202 D204 D237 E11 E69 D96 Q97 D99 D132
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0031386 protein tag activity
GO:0042802 identical protein binding
GO:0044389 ubiquitin-like protein ligase binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0016925 protein sumoylation
GO:0098609 cell-cell adhesion
Cellular Component
GO:0000794 condensed nuclear chromosome
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005940 septin ring
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vel, PDBe:6vel, PDBj:6vel
PDBsum6vel
PubMed36157596
UniProtP12830|CADH1_HUMAN Cadherin-1 (Gene Name=CDH1);
Q12306|SMT3_YEAST Ubiquitin-like protein SMT3 (Gene Name=SMT3)

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