Structure of PDB 6vc8 Chain C

Receptor sequence
>6vc8C (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDSYRKQVVIDGETCLLDILDT
AQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKC
DLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKE
3D structure
PDB6vc8 Machine learning-driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP C G13 V14 G15 K16 S17 A18 F28 N116 K117 D119 S145 A146 G13 V14 G15 K16 S17 A18 F28 N98 K99 D101 S127 A128
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vc8, PDBe:6vc8, PDBj:6vc8
PDBsum6vc8
PubMed34983849
UniProtP01116|RASK_HUMAN GTPase KRas (Gene Name=KRAS)

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