Structure of PDB 6v0q Chain C

Receptor sequence
>6v0qC (length=117) Species: 9606 (Homo sapiens) [Search protein sequence]
EQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTM
KEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKI
LSQERIQSLKQSIDFMA
3D structure
PDB6v0q Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
ChainC
Resolution1.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 EAE C F156 I164 N211 Y217 F25 I33 N80 Y86 MOAD: Kd=4200nM
BindingDB: Kd=4600nM
External links
PDB RCSB:6v0q, PDBe:6v0q, PDBj:6v0q
PDBsum6v0q
PubMed32091206
UniProtQ9NPI1|BRD7_HUMAN Bromodomain-containing protein 7 (Gene Name=BRD7)

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