Structure of PDB 6uqg Chain C

Receptor sequence
>6uqgC (length=530) Species: 9606 (Homo sapiens) [Search protein sequence]
MQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRF
YWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMN
FRTGTVNSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGALR
IVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTDDLASAVVRIFNLIGMM
LLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSH
MLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRR
QYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELND
PLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIRE
GAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGEICLLTKGRRTASVRA
DTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKF
QKDLNTGVFNNQENEILKQIVKHDREMVQA
3D structure
PDB6uqg Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
ChainC
Resolution3.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP C V522 M530 F538 G539 I541 C542 R549 T550 R590 V633 V417 M425 F433 G434 I436 C437 R444 T445 R485 V528
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006813 potassium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6uqg, PDBe:6uqg, PDBj:6uqg
PDBsum6uqg
PubMed31787376
UniProtO60741|HCN1_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Gene Name=HCN1)

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