Structure of PDB 6tz7 Chain C

Receptor sequence
>6tz7C (length=117) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
KIEWHEGVTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGSKFDSSVDRNE
PFQTQIGTGRVIKGWDEGVPQMSLGEKAVLTITPDYGYGARGFPPVIPGN
STLIFEVELLGINNKRA
3D structure
PDB6tz7 Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FK5 C Y27 D38 R43 F47 R55 V56 I57 W60 Y83 F100 Y32 D43 R48 F52 R60 V61 I62 W65 Y88 F105
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:6tz7, PDBe:6tz7, PDBj:6tz7
PDBsum6tz7
PubMed31537789
UniProtQ4WLV6|FKB1A_ASPFU FK506-binding protein 1A (Gene Name=fpr1A)

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