Structure of PDB 6tu4 Chain C

Receptor sequence
>6tu4C (length=372) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
DVQALVVDNGSGNVKAGVAGDDAPRSVFPSIVGRPKNPGIMVGMEEKDAF
VGDEAQTKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRAAPEEHPV
LLTEAPLNPKGNRERMTQIMFESFNVPAMYVAIQAVLSLYSSGRTTGIVL
DSGDGVSHTVPIYEGYALPHAIMRLDLAGRDLTEYLMKILHERGYGFSTS
AEKEIVRDIKEKLCYIALNFDEEMKTSEQSSDIEKSYELPDGNIITVGNE
RFRCPEALFQPSFLGKEAAGIHTTTFNSIKKCDVDIRKDLYGNIVLSGGT
TMYEGIGERLTRDITTLAPSTMKIKVVAPPERKYSVWIGGSILSSLSTFQ
QMWITKEEYDESGPSIVHRKCF
3D structure
PDB6tu4 High-resolution structures of malaria parasite actomyosin and actin filaments.
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9UE C G198 Y199 G200 E206 L243 G194 Y195 G196 E202 L239
BS02 ADP C G14 G16 N17 K19 G157 D158 K214 E215 G303 Y307 G10 G12 N13 K15 G153 D154 K210 E211 G299 Y303
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0007010 cytoskeleton organization
GO:0009665 plastid inheritance
GO:0020014 schizogony
GO:0070360 symbiont-mediated actin polymerization-dependent cell-to-cell migration in host
GO:0085017 entry into host cell by a symbiont-containing vacuole
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6tu4, PDBe:6tu4, PDBj:6tu4
PDBsum6tu4
PubMed35377914
UniProtQ8I4X0|ACT1_PLAF7 Actin-1 (Gene Name=ACT1)

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