Structure of PDB 6ttk Chain C

Receptor sequence
>6ttkC (length=284) Species: 9606 (Homo sapiens) [Search protein sequence]
ANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLH
DRIYVIGGYDGRSRLSSVECLDYTGVWYSVAPMNVRRGLAGATTLGDMIY
VSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLG
GYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFD
GTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNS
LLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLR
3D structure
PDB6ttk Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12.
ChainC
Resolution2.383 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C F289 Y321 I439 F481 H486 Y512 Y528 F11 Y43 I157 F199 H204 Y230 Y246
External links
PDB RCSB:6ttk, PDBe:6ttk, PDBj:6ttk
PDBsum6ttk
PubMed32574548
UniProtQ53G59|KLH12_HUMAN Kelch-like protein 12 (Gene Name=KLHL12)

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