Structure of PDB 6t48 Chain C

Receptor sequence
>6t48C (length=243) Species: 1330520 (Enterovirus F) [Search protein sequence]
GIPTLYTPGSGQFLTTDDFQTPCMLPKFQPTPVIDIPGEVKNFLEVVQVE
SLVEINNVESAEGVARYRIPLNVQDAMDGQIMALRVDPGIDGPMQSTLLG
VFTRYYAQWSGSLDFTFMFCGTFMTTGKVIIAYTPPGGDQPTNRRQAMLG
THVVWDFGLQSSITLVVPWISSGHFRGTTLENTIYKYRYYEAGYITMWYQ
TNMVVPPNFPTTASILMFVAAQPNFSLRILKDRPDISQEGALQ
3D structure
PDB6t48 Glutathione facilitates enterovirus assembly by binding at a druggable pocket.
ChainC
Resolution2.17 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH C Q238 G240 Q238 G240
BS02 GLY C Q95 D235 Q95 D235
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6t48, PDBe:6t48, PDBj:6t48
PDBsum6t48
PubMed31909201
UniProtQ2LKZ0

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