Structure of PDB 6t2b Chain C

Receptor sequence
>6t2bC (length=436) Species: 239935 (Akkermansia muciniphila) [Search protein sequence]
IPAGDHLWKSAPRPSGSTYMGGFKAPRLGRIRLAFIGVGGRGFSHLAQMC
VMDGVEIVGICDLKEELTKRGVDRVLSRMGKSPLGYSGGDMEYLTMLKEL
KPDAVIISTDWSSHARIACDSMKHGAHAFVEVPLAVSLEELWSLVDTSEA
TRKHCMMMENVNYGRDELMFLNMVRQGVIGDLLHGEAAYIHCLVTQLGDT
RGEGAWRPEYHTRINGNLYPTHGLGPVAQYMNLERGEDRFCRVAAFASPA
LGRNAYAKKHLPADHRWNNTPFICGDMNTAVVKTQLGRTILVQLDETSPR
PYSRANLIQGTEGTLAGFPTRVAGEKLGNGNYHEWIEGREKLAAIYEKYD
HPLWKRIGELATKMGGHGGMDFVMLSRIVECLRNGEPMDQNVYEGASWSS
LLPLTARSIAQGGMPVEFPDFTRGDWKTTMPLAVVS
3D structure
PDB6t2b The Catalytic Acid-Base in GH109 Resides in a Conserved GGHGG Loop and Allows for Comparable alpha-Retaining and beta-Inverting Activity in an N-Acetylgalactosaminidase from Akkermansia muciniphila
ChainC
Resolution2.13 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD C G77 R78 D99 L100 D127 S145 T146 W148 H151 E168 V169 N197 E240 W243 Y256 H259 H404 G40 R41 D62 L63 D90 S108 T109 W111 H114 E131 V132 N160 E203 W206 Y219 H222 H367
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:6t2b, PDBe:6t2b, PDBj:6t2b
PDBsum6t2b
PubMed
UniProtB2UQL7|G1092_AKKM8 Glycosyl hydrolase family 109 protein 2 (Gene Name=Amuc_0920)

[Back to BioLiP]