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BioLiP

Structure of PDB 6s0w Chain C

Receptor sequence
>6s0wC (length=277) Species: 1967 (Streptomyces kanamyceticus) [Search protein sequence]
MALAAPPGELTLALTPDDKTLDPASLDRALAILAEHGILVLTGMLRTRLT
DQLRTAMLDDLPEVLRQQDVPTNFVPGHVQQDPPVRESLLFPDVLLNPVV
YQITHAVLGADARNAVYSGNMNLPGSHEQPVHLDEPHLWPGISHPPYCLC
VDVPLIDFTLENGSTEYWPGSHVLNPDECYDERGCVLPAELERRRAVAPP
VRFPIPVGSVVIRDGRLWHRGVPNLSAAPRPLLAMTHYTEWFDMPPIQLP
DTVKSWVDGSDRHTHAHFVAGDVDHLT
3D structure
PDB6s0w A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates.
ChainC
Resolution2.36 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.37: kanamycin B dioxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9CS C N73 N120 D134 E135 R183 N73 N120 D134 E135 R183
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:1901133 kanamycin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6s0w, PDBe:6s0w, PDBj:6s0w
PDBsum6s0w
PubMed32592631
UniProtQ6L732|KANJ_STRKN Kanamycin B dioxygenase (Gene Name=kanJ)

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