Structure of PDB 6rt8 Chain C

Receptor sequence
>6rt8C (length=314) Species: 4058 (Catharanthus roseus) [Search protein sequence]
DETIWDLSPYIKIFKDGRVERLHNSPYVPPSLNDPETGVSWKDVPISSQV
SARVYIPKISDHEKLPIFVYVHGAGFCLESAFRSFFHTFVKHFVAETKVI
GVSIEYRLAPEHLLPAAYEDCWEALQWVASHVGLDTAIDKDPWIINYGDF
DRLYLAGDSPGANIVHNTLIRAGKEKLKGGVKILGAILYYPYFIIPTSTK
LSDDFEYNYTCYWKLAYPNAPGGMNNPMINPIAENAPDLAGYGCSRLLVT
LVSMISTTPDETKDINAVYIEALEKSGWKGELEVADFDADYFELFTLETE
MGKNMFRRLASFIK
3D structure
PDB6rt8 Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids.
ChainC
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KJE C Y18 H31 A82 G83 S172 P173 Y205 F218 Y225 I268 Y304 Y10 H23 A74 G75 S159 P160 Y192 F205 Y212 I255 Y291
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016829 lyase activity
Biological Process
GO:0009820 alkaloid metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6rt8, PDBe:6rt8, PDBj:6rt8
PDBsum6rt8
PubMed32066966
UniProtA0A2P1GIW2|CS_CATRO Catharanthine synthase (Gene Name=CS)

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