Structure of PDB 6rjr Chain C

Receptor sequence
>6rjrC (length=500) Species: 28985 (Kluyveromyces lactis) [Search protein sequence]
HPTNTADVRKDRVVTNSQGAPINEPFATQRVGQHGPLLLQDFNLLDSLAH
FNRERIPERNPHAHGSGAFGYLEITDDITDVCGSAMFDTVGKRTRCLVRF
STVGGEKGSADTARDPRGFAIKFYSEEGNVDWVNNNTPVFFIRDPSKFPH
FIHTQKRNPETNMKDADMFWDFLTTEENQVAIHQVMILFSDRGTPASYRN
MNSYSGHTYKWSNKQGEWRYVQVHLKTDQGIKNLNNEEATKLAGENPDYC
QKDLFENIAKGNYPSWTLYIQTMTEEEAEKLPFSVFDLTKVWPHKQFPLR
RVGKMVLNENPENYFAQVEQAAFSPSHTVPYQEASADPVLQARLFSYPDA
HRYRLGPNYSQIPVNCPYASKVFNPAIRDGPMNVNGNLGKEPNYLSTSKK
YQFIQQSKPIQQHQEVWSGPAMPVHWATSPGDIDFVQARDLYNKVLSKQP
GQQKALAHNVAVHVASACPEIQDRVFAMFARVDRGLSENIKKEALSLSPR
3D structure
PDB6rjr Peroxisomal catalases from the yeasts Pichia pastoris and Kluyveromyces lactis as models for oxidative damage in higher eukaryotes.
ChainC
Resolution1.895 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.1.6: catalase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM C R61 N62 H64 R101 N137 F150 F325 V341 R345 Y349 H353 R356 R59 N60 H62 R99 N135 F148 F323 V339 R343 Y347 H351 R354
BS02 NDP C P140 H185 S192 R194 K228 V293 P295 H296 Q439 L443 V447 Q451 P138 H183 S190 R192 K226 V291 P293 H294 Q437 L441 V445 Q449
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004096 catalase activity
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006979 response to oxidative stress
GO:0042542 response to hydrogen peroxide
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005777 peroxisome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6rjr, PDBe:6rjr, PDBj:6rjr
PDBsum6rjr
PubMed31238127
UniProtQ6CR58

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