Structure of PDB 6rfx Chain C

Receptor sequence
>6rfxC (length=403) Species: 36809 (Mycobacteroides abscessus) [Search protein sequence]
ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHD
GKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQ
LADIRSRGESLAMLFASYGRFGYGVATESAELSGQVRELAFRPTVDLGDG
TLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKES
GKVRFVLHYESDGTASGFAIYRPKPGWGGPNAELHVQEVLGTNPRSYART
WRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIP
RALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADI
ALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAP
DDF
3D structure
PDB6rfx Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
ChainC
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P4K C Q279 S374 A396 Q271 S366 A388
BS02 P4K C Y23 F26 D410 Y21 F24 D402
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0034069 aminoglycoside N-acetyltransferase activity
Biological Process
GO:0030649 aminoglycoside antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6rfx, PDBe:6rfx, PDBj:6rfx
PDBsum6rfx
PubMed31254444
UniProtA0A1M9A4M7

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