Structure of PDB 6rft Chain C

Receptor sequence
>6rftC (length=403) Species: 36809 (Mycobacteroides abscessus) [Search protein sequence]
SELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFH
DGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRH
QLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTV
DLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEE
LQKESGKVRFVLHYESDGTASGFAIYRPKPNAELHVQEVLGTNPRSYART
WRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIP
RALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADI
ALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAP
DDF
3D structure
PDB6rft Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO C V83 V85 R90 R91 G93 L95 T96 L116 F117 S119 E120 I123 Y124 R126 V82 V84 R89 R90 G92 L94 T95 L115 F116 S118 E119 I122 Y123 R125
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0034069 aminoglycoside N-acetyltransferase activity
Biological Process
GO:0030649 aminoglycoside antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6rft, PDBe:6rft, PDBj:6rft
PDBsum6rft
PubMed31254444
UniProtA0A1M9A4M7

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