Structure of PDB 6r2u Chain C

Receptor sequence
>6r2uC (length=272) Species: 9606 (Homo sapiens) [Search protein sequence]
DGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLW
RQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCE
IENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVY
VQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLK
CLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQD
TAPYSCHVQHSSLAQPLVVPWE
3D structure
PDB6r2u Crystal structure of zinc-alpha 2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding.
ChainC
Resolution2.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 11D C E151 V153 Y154 E147 V149 Y150 MOAD: Kd=0.51uM
BS02 11D C L69 R73 W115 V153 Y154 R157 L65 R69 W111 V149 Y150 R153 MOAD: Kd=0.51uM
BS03 11D C R73 I76 Y117 W148 Y154 R69 I72 Y113 W144 Y150 MOAD: Kd=0.51uM
Gene Ontology
Molecular Function
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0008320 protein transmembrane transporter activity
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0008285 negative regulation of cell population proliferation
GO:0071806 protein transmembrane transport
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0009897 external side of plasma membrane
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6r2u, PDBe:6r2u, PDBj:6r2u
PDBsum6r2u
PubMed31506272
UniProtP25311|ZA2G_HUMAN Zinc-alpha-2-glycoprotein (Gene Name=AZGP1)

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