Structure of PDB 6qcx Chain C

Receptor sequence
>6qcxC (length=733) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search protein sequence]
GMTLAKIELLKQLLRDNEAKTVLKQTTVDQYNIIRKFNTSRIEKNPSLRM
KWAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVT
WWNTYGPIGDTEGFERVYESFFLRKMRLDNATWGRITFGPVERVRKRVLL
NPLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTM
ITPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPG
GNKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSC
LAAIDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIG
NGTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDL
IILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFD
QWGYEESPKASELHGINESMNASDYTLKGVVVTRNVTEKVSITKNLSLIK
RTGEVIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQNTYQWVLKN
LVTLKAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARAVLKQMRDQ
EVMKTDQFIKLLPFCFSPPKLRSNGEPYQFLKLVLKGGGENFIEVRKGSP
LFSYNPQTEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPD
LGDFKTIEELEKLKPGEKANILLYQGKPVKVVK
3D structure
PDB6qcx Structural snapshots of actively transcribing influenza polymerase.
ChainC
Resolution3.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C P45 R146 R217 Q259 I262 R266 Q325 R326 K341 W359 E363 K378 F406 R425 Y434 R438 S520 L522 S524 P46 R147 R218 Q260 I263 R267 Q326 R327 K342 W360 E364 K379 F407 R426 Y435 R439 S513 L515 S517
BS02 rna C R40 E42 K43 R48 W51 R218 R41 E43 K44 R49 W52 R219
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qcx, PDBe:6qcx, PDBj:6qcx
PDBsum6qcx
PubMed31160782
UniProtQ5V8X3

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