Structure of PDB 6q1s Chain C

Receptor sequence
>6q1sC (length=283) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
AMVVTLDGEILQPGMPLLHADDLAAVRGDGVFETLLVRDGRACLVEAHLQ
RLTQSARLMDLPEPDLPRWRRAVEVATQRWVASTADEGALRLIYSRGREG
GSAPTAYVMVSPVPARVIGARRDGVSAITLDRGLPADGGDAMPWLIASAK
TLSYAVNMAVLRHAARQGAGDVIFVSTDGYVLEGPRSTVVIATDPCLLTP
PPWYPILRGTTQQALFEVARAKGYDCDYRALRVADLFDSQGIWLVSSMTL
AARVHTLDGRRLPRTPIAEVFAELVDAAIVSDR
3D structure
PDB6q1s A hypothetical aminotransferase from Mycobacterium tuberculosis
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.21: D-amino-acid transaminase.
4.1.3.38: aminodeoxychorismate lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PMP C R50 K149 Y153 P184 R185 S186 T187 L213 G215 T216 T217 S252 S253 R51 K150 Y154 P185 R186 S187 T188 L207 G209 T210 T211 S246 S247
BS02 AKG C M254 T255 M248 T249
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0008696 4-amino-4-deoxychorismate lyase activity
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process
GO:0046654 tetrahydrofolate biosynthetic process
GO:0046656 folic acid biosynthetic process
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6q1s, PDBe:6q1s, PDBj:6q1s
PDBsum6q1s
PubMed
UniProtQ79FW0|BALDT_MYCTU Bifunctional aminodeoxychorismate lyase / D-amino acid transaminase (Gene Name=Rv0812)

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