Structure of PDB 6pht Chain C

Receptor sequence
>6phtC (length=343) Species: 1658765 (Marinobacter subterrani) [Search protein sequence]
SMKTVFSPLHSRRHVKTELDGGLLIEPHEKPSRAETILARVKDQALGEIL
EPEEFGLGPVKRVHTADYVSFLETCWDEWVAAGKRGEAIPTFWVGRGMRA
RLPKDIDGRLGYYSLGADTSISDGTWEAARASANVALTAQKLVAEGERAA
FALCRPPGHHAHADVFGGYCFFNNAAIAAQAFRDQGYGKVAVLDVDFHHG
NGTQAIFYDRSDVLTISLHGDPDLVFPHFLGFEDETGEGDGEAYNLNIVF
PPDTPFSIWSQGLEKACERIRTFAPDALVVALGVDTFEEDPISFFKLTSG
DYLKLGKRLEQLGLPTVFTMEGGYDVDAIGVNAVNVMQGFEGK
3D structure
PDB6pht Structure and Function of the Acetylpolyamine Amidohydrolase from the Deep Earth HalophileMarinobacter subterrani.
ChainC
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OKP C D117 H158 H159 G167 Y168 D195 H197 F225 D284 G321 Y323 D118 H159 H160 G168 Y169 D196 H198 F226 D285 G322 Y324 MOAD: ic50=390uM
BS02 MG C D104 D106 D105 D107
BS03 ZN C D195 H197 D284 D196 H198 D285
Gene Ontology
Molecular Function
GO:0004407 histone deacetylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006338 chromatin remodeling

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6pht, PDBe:6pht, PDBj:6pht
PDBsum6pht
PubMed31436969
UniProtA0A0J7JFD7

[Back to BioLiP]