Structure of PDB 6pfz Chain C

Receptor sequence

>6pfzC (length=535) Species: 224325 (Archaeoglobus fulgidus DSM 4304)

MNVVVIGGGAAGLKAASRIRRKDGDASITVVEAGKYVSLGRCGLPYYVGG
LVHEVDNLRETRDEAYFKKLKNIDVLTETVATEIDRSRKTVKIVRNGSED
ELNYDYLVIATGARPAKPPIEGIEAEGVVTLTSAEEAEKIIEMWEEGAEK
AVVIGAGFIGLESAEALKNLDMEVTVIEMMDRVAPAMLDREMAVLVENHL
REKGVNVVTSTRVEKIVSQDDKVRAVINGKEYPADVVVVATGIKPNSELA
EKAGLKIGETGAIWVDEYMRTSDESIYAGGDCVETTCLVTGKKIIAPFGD
VANKQGRVIGENITGGRAVFPGVIRTAIFKVFDFTAASAGVNEQMAKEAG
LDYFTVIAPSPDRAHYYPQANYIRLKLIVEKGSWRVIGAQGVGMGEVAKR
IDVLSTAIQAGMTIDQLANLDLAYAPPYSPALDPVITIANVAMNKRDGLF
EGINVFELKEIVILDVRSEEEFKTRRKVIHIPILELRERLDEIPRDKEIV
VVCAIGLRSFEASRILKHAGFEKVKILEGGMAFWF

3D structure

• PDB: 6pfz Structural and Kinetic Characterization of Hyperthermophilic NADH-Dependent Persulfide Reductase from Archaeoglobus fulgidus .
• Chain: C
• Resolution: 3.10004 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): V37 C42 L455 F456
• Catalytic site (residue number reindexed from 1): V37 C42 L449 F450

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	C	Y430 A431	Y424 A425
BS02	COA	C	A364 Y372 Y430 N450 L523 F526	A358 Y366 Y424 N444 L507 F510
BS03	FAD	C	G7 G9 A11 E32 A33 R41 C42 A86 T116 L136 D287 P303 F304 G305	G7 G9 A11 E32 A33 R41 C42 A81 T111 L131 D281 P297 F298 G299
BS04	COA	C	K14 R18 R21 S38 G40 C42 R67 K76 R313	K14 R18 R21 S38 G40 C42 R62 K71 R307
BS05	CA	C	D427 L428	D421 L422
BS06	CA	C	D306 T332	D300 T326

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:6pfz, PDBe:6pfz, PDBj:6pfz
• PDBsum: 6pfz
• PubMed: 33776585
• UniProt: O29847