Structure of PDB 6par Chain C

Receptor sequence

>6parC (length=573) Species: 279238 (Novosphingobium aromaticivorans DSM 12444)

YLWPADNAVLRRRVVGAILMVLLGKATTLALPFAYKKAVDAMTLGGGAQP
ALTVALAFVLAYALGRFSGVLFDNLRNIVFERVGQDATRHLAENVFARLH
KLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNIAPTVIELTAVIVI
FWLNFGLGLVTATILAVIAYVWTTRTITEWRTHLREKMNRLDGQALARAV
DSLLNYETVKYFGAESREEARYASAARAYADAAVKSENSLGLLNIAQALI
VNLLMAGAMAWTVYGWSQGKLTVGDLVFVNTYLTQLFRPLDMLGMVYRTI
RQGLIDMAEMFRLIDTHIEVADVPNAPALVVNRPSVTFDNVVFGYDRDRE
ILHGLSFEVAAGSRVAIVGPSGAGKSTIARLLFRFYDPWEGRILIDGQDI
AHVTQTSLRAALGIVPQDSVLFNDTIGYNIAYGRDGASRAEVDAAAKGAA
IADFIARLPQGYDTEVGERGLKLSGGEKQRVAIARTLVKNPPILLFDEAT
SALDTRTEQDILSTMRAVASHRTTISIAHRLSTIADSDTILVLDQGRLAE
QGSHLDLLRRDGLYAEMWARQAA

3D structure

• PDB: 6par A structural framework for unidirectional transport by a bacterial ABC exporter.
• Chain: C
• Resolution: 3.35 Å

Enzymatic activity

• Enzyme Commision number: 7.-.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ANP	C	Y370 R374 S396 G397 G399 K400 S401 T402 Q442	Y345 R349 S371 G372 G374 K375 S376 T377 Q417
BS02	MG	C	S401 Q442	S376 Q417
BS03	ANP	C	K497 S499 E502	K472 S474 E477

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0042626 ATPase-coupled transmembrane transporter activity
• GO:0140359 ABC-type transporter activity

Biological Process

• GO:0006811 monoatomic ion transport
• GO:0046689 response to mercury ion
• GO:0055085 transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:6par, PDBe:6par, PDBj:6par
• PDBsum: 6par
• PubMed: 32703810
• UniProt: Q2G506|ATM1_NOVAD ATM1-type heavy metal exporter (Gene Name=atm1)