Structure of PDB 6p8t Chain C

Receptor sequence
>6p8tC (length=320) Species: 575584 (Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841) [Search protein sequence]
MRVTMSLEALTTEALAAIAAAQDLVALDQVRVQFTGKKSQLAEQSKALGK
MDPEERKVQGAAIHAVRETINNALTERQTALQQAALAQKLASETIDITLP
GRGQRIGTVHPVTQVQERICQFFTKAGFTVATGPEVEDDYHNFEALNIDT
FYFDANHLLRTHTSGVQIRTMETSQPPIRIVCPGRVYRCDSDQTHSPMFH
QIEGLYVAENTSFAELKGLLINLLNEFFEKDLKVRFRPSYFPFTEPSAEV
DIMDERGRWLEVLGCGMVHPNVLRAAGIDPDKYKGFAFGLGVERFAMLRY
GINDLRMFYQNDVRFLRQFA
3D structure
PDB6p8t Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase.
ChainC
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.20: phenylalanine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NO4 C S174 Q177 E213 F251 F253 G274 C275 F298 S164 Q167 E203 F241 F243 G264 C265 F288
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0006432 phenylalanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6p8t, PDBe:6p8t, PDBj:6p8t
PDBsum6p8t
PubMed33411531
UniProtD0CA72

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