Structure of PDB 6p4j Chain C

Receptor sequence
>6p4jC (length=502) Species: 223997 (Murine norovirus 1) [Search protein sequence]
AVPIQPVAGAALAAPAAGQINQIDPWIFQNFVQCPLGEFSISPRNTPGEI
LFDLALGPGLNPYLAHLSAMYTGWVGNMEVQLVLAGNAFTAGKVVVALVP
PYFPKGSLTTAQITCFPHVMCDVRTLEPIQLPLLDVRRVLWHATQDQEES
MRLVCMLYTPLRTNSPGDESFVVSGRLLSKPAADFNFVYLTPPIERTIYR
MVDLPVIQPRLCTHARWPAPVYGLLVDPSLPSNPQWQNGRVHVDGTLLGT
TPISGSWVSCFAAEAAYEFQSGTGEVATFTLIEQDGSAYVPGDRAAPLGY
PDFSGQLEIEVQTETTKTGDKLKVTTFEMILGPTTNADQAPYQGRVFASV
TAAASLDLVDGRVRAVPRSIYGFQDTIPEYNDGLLVPLAPPIGPFLPGEV
LLRFRTYMRQIDTADAAAEAIDCALPQEFVSWFASNAFTVQSEALLLRYR
NTLTGQLLFECKLYNEGYIALSYSGSGPLTFPTDGIFEVVSWVPRLYQLA
SV
3D structure
PDB6p4j Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion.
ChainC
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CHO C Y250 Y435 R437 Y222 Y407 R409
BS02 CHO C Q340 R390 V391 R392 V394 Q312 R362 V363 R364 V366
Gene Ontology
Biological Process
GO:0019049 virus-mediated perturbation of host defense response
Cellular Component
GO:0044423 virion component

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6p4j, PDBe:6p4j, PDBj:6p4j
PDBsum6p4j
PubMed31341042
UniProtQ2V8W4

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