Structure of PDB 6ovr Chain C

Receptor sequence
>6ovrC (length=1107) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRE
TFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGL
IKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGR
YIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETL
ARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYV
YGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTL
RYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRE
RMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHK
RRISALGPGGLTRFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARV
DELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAE
RVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMG
SNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRI
VVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPAS
ENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIE
ARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSF
KGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDP
GVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHL
PDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKE
PEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEE
QLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTG
PYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIE
GRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDI
FEGLASK
3D structure
PDB6ovr Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
ChainC
Resolution2.843 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R134 F394 G1023 K1024 Q1030 R1031 M1035 R127 F387 G1012 K1013 Q1019 R1020 M1024
BS02 rna C Q390 Q393 F394 L413 T419 R420 I452 K838 K846 H999 Q383 Q386 F387 L406 T412 R413 I441 K827 K835 H988
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ovr, PDBe:6ovr, PDBj:6ovr
PDBsum6ovr
PubMed31965171
UniProtQ8RQE9|RPOB_THET8 DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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