Structure of PDB 6om2 Chain C

Receptor sequence
>6om2C (length=596) Species: 9606 (Homo sapiens) [Search protein sequence]
FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGI
VEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS
KQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD
GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVY
SIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTL
GMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLF
MDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDL
DQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSG
CPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEV
YPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLL
DKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFR
DKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLT
3D structure
PDB6om2 General structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
ChainC
Resolution2.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C Y178 D218 Y178 D218
BS02 MAN C E538 I540 E538 I540
BS03 CA C D230 N232 D234 I236 D238 D230 N232 D234 I236 D238
BS04 CA C D284 N286 D288 Y290 D292 D284 N286 D288 Y290 D292
BS05 CA C D349 D351 D353 F355 D357 D349 D351 D353 F355 D357
BS06 CA C D414 D416 N418 Y420 D422 D414 D416 N418 Y420 D422
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6om2, PDBe:6om2, PDBj:6om2
PDBsum6om2
PubMed31792290
UniProtP06756|ITAV_HUMAN Integrin alpha-V (Gene Name=ITGAV)

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