Structure of PDB 6o96 Chain C

Receptor sequence
>6o96C (length=107) Species: 8355 (Xenopus laevis) [Search protein sequence]
AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAE
ILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNI
QSVLLPK
3D structure
PDB6o96 Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination.
ChainC
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R29 R42 V43 G44 A45 K75 T76 R77 R18 R31 V32 G33 A34 K64 T65 R66 PDBbind-CN: Kd=50nM
BS02 dna C K15 R17 R20 R32 R77 K4 R6 R9 R21 R66 PDBbind-CN: Kd=50nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6o96, PDBe:6o96, PDBj:6o96
PDBsum6o96
PubMed30981630
UniProtP06897|H2A1_XENLA Histone H2A type 1

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