Structure of PDB 6o8g Chain C

Receptor sequence

>6o8gC (length=560) Species: 1395 ([Bacillus] caldotenax)

GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNV
IAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYDYKINDEID
KLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERN
ALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDE
IERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEER
LAELRAQGKLLEAQRLEQRTRYDLEMMSSGIENYSRHLALRPPGSTPYTL
LDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNR
PLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVR
PTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYL
HSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKE
GFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQE
EYNRKHGIVP

3D structure

• PDB: 6o8g Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System.
• Chain: C
• Resolution: 2.64 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	C	N66 K67 C91 S141 R289 Q346 R357 K358 L361 F366 K455 S477 R484 N503 L504 F527	N64 K65 C89 S121 R269 Q321 R332 K333 L336 F341 K430 S452 R459 N478 L479 F502
BS02	dna	C	Y292 P345 G349 G353 R357 G526 F527	Y272 P320 G324 G328 R332 G501 F502
BS03	ADP	C	Y11 Q14 Q17 G42 G44 K45 F47 P414 R543	Y9 Q12 Q15 G40 G42 K43 F45 P389 R518

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006289 nucleotide-excision repair

Cellular Component

• GO:0009380 excinuclease repair complex

External links

• PDB: RCSB:6o8g, PDBe:6o8g, PDBj:6o8g
• PDBsum: 6o8g
• PubMed: 31549070
• UniProt: P56981|UVRB_BACCA UvrABC system protein B (Gene Name=uvrB)